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Best Hospitals for Bone marrow transplant in India


  •  Bone Marrow Transplantation

    The spongy tissue inside the bone is called as the bone marrow. Bone marrow is responsible for the generation of various types of blood cells like RBCs, WBCs and platelets that carry out various important functions. Due to certain diseases affecting the bone marrow, the production of blood cells is interfered with, leading to various serious and potentially fatal complications. In these situations, bone marrow transplantation is the only option to save one’s life.

    Now let’s look at the various disorders that can affect the bone marrow:

    The most common disorders that affect the bone marrow are the various types of bone marrow cancer. Some of the most important types of Bone Marrow Cancer are:

    1. Multiple Myeloma occurs in the plasma cells and is the most common. It is predominantly seen in males over the age of 65.

    2. Lymphomas are of two types- Hodgkins and Non-Hodgkins lymphomas. Increased age, exposure to chemicals, radiation, chemotherapy, HIV infections, obesity etc are known risk factors.

    3. Leukaemia is of two types-Myeloid or lymphocytic and could be acute or chronic. Acute myeloid leukaemia (AML), chronic myeloid leukaemia (CML), acute lymphocytic leukaemia (ALL) and chronic lymphocytic leukaemia (CLL).

    Symptoms of bone marrow cancer:

    Symptoms may vary depending upon the type of cancer and may vary from person to person. Some of the common symptoms are:

    • Persistent and recurrent fever

    • Loss of weight

    • Loss of appetite

    • Fatigue

    • Pain in the back

    • Tenderness of the bones

    • Swelling of the bones 

    • Increased susceptibility to fractures of the bone

    • Anaemia

    • Recurrent infections

    • Shortness of the breath

    There are certain other diseases affecting the bone marrow that could warrant bone marrow transplantation. Some of them are:

    • Aplastic anaemia

    • Thalassemia’s

    • Sickle cell anaemia

    • Bone Marrow depression resulting from radiation or chemotherapy treatments

    All these situations are dire and the patients require transplantation of the bone marrow at the earliest. Bone marrow transplantation procedure is undertaken in all major medical institutions around the world but the cost of the procedure varies significantly from country to country. Bone Marrow transplant cost in India is one of the lowest among medically advanced countries where the facilities are available. There are many super speciality hospitals that offer bone marrow transplant in India with a very high degree of success.

    Types of bone marrow/Stem cell transplant and bone marrow transplant procedure:

    There are various methods of bone marrow transplant depending on the source of the bone marrow:

    • Autologous transplant: In an autologous transplant, the bone marrow is sourced from one’s own body and is ideal for situations where the patient may suffer from bone marrow depression because of radiation or chemotherapy. Functional stem cells are sourced from the large bones prior to the treatment and reintroduced into the body after the treatment is over.

    • Allogeneic transplant: In an allogeneic transplant, bone marrow donation is done by another person who is genetically similar to the person who needs the transplant. Usually, close relatives like siblings, parents etc are the ideal donors but in certain cases, non-relatives may also qualify as potential donors. The bone marrow is harvested from the donor by using special syringes and needles from the hip bones under general anaesthesia. It is then transplanted to the recipient. 

    • Cord blood transplant: Placental cord blood is harvested and stored for potential use in the future. These placental stem cells are then used if any necessities arise in the future.

    • Peripheral blood stem cell transplant: done by a process called Apheresis where blood is taken out from the donor to extract the stem cells by passing it through special apparatus through an IV line starting from one arm and reintroduced into the body through an IV line in the other arm. The procedure is repeated until an adequate amount of stem cells are harvested. These stem cells are transplanted to the recipients for the regeneration of a healthy bone marrow.

    Prior to transplantation procedure, radiation or chemotherapy is performed with the aim of destroying the diseased bone marrow and other cancer cells to make space for the transplanted bone marrow. Immuno-suppressants are also administered to reduce the immunity of the body to prevent the rejection of the bone marrow graft.

    Risks and complications:

    • Graft Versus Host Disease (GVHD) where donor cells attack the recipient's body cells

    • Graft failure

    • Occurrence of internal Bleeding problems

    • Development of cataracts

    • Anaemia 

    • Side effects like decreased blood pressure, headaches, nausea, pain, shortness of breath, chills, fever might occur frequently

    Dos and Don’ts:

    Dos:

    • Take medicines as prescribed

    • Follow guidelines prescribed for healthy diet and food handling

    • Give enough rest to the body

    Don’ts:

    • Don’t expose yourself to situations that can cause an infection

    • Don’t ignore the mildest of infections

    • Don’t ignore symptoms of GVHD like skin blisters, rashes, nausea, jaundice etc.

     

Bone marrow transplant cost in India:

Approximate Cost (USD) Days in Hospital Days in India
417 - 596 (21 - 28 ) 60 - 75 days
Bone marrow transplant cost in India:

Approximate Cost (USD) Days in Hospital Days in India
417 - 596 (21 - 28 ) 60 - 75 days

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  • Apollo Indraprastha
    Location
    Nearest Airport New Delhi ( 20 km)
    • Multi-specialty hospital established in year 1996
    • Flagship hospital of Apollo Hospitals group
    • First JCI accredited hospital in India

    • Bone marrow, peripheral blood and cord blood transplants
    • Facility for stem cell collection, processing, storage and infusion
    Details
  • Apollo Chennai
    Location
    Nearest Airport Chennai ( 22 km)
    • Multi-specialty hospital established in year 1983
    • First hospital of Apollo Hospitals group
    • JCI and NABH accredited
    Details
  • Fortis Mulund
    Location
    Nearest Airport Mumbai ( 17 km)
    • Multi-specialty hospital established in year 2002
    • Part of Fortis Healthcare Group
    • JCI and NABH accredited
    Details
  • Wockhardt
    Location
    Nearest Airport Mumbai ( 18 km)
    • Flagship hospital of Wockhardt Group
    • JCI accredited hospital in Mumbai
    • Latest and largest flagship JCI hospital of Wockhardt Group

    • Latest INGENIA 3.0 Tesla Digital Broadband MRI system
    • Worlds fastest CT Scan Machine-Brilliance iCT Essential 356 Slice CT
    • 4D Sonography with Fusion & Navigation System Digital Dexa Scan
    Details
  • Columbia Asia
    Location
    Nearest Airport Bangalore ( 32 km)
    • Multispecialty hospital established in 2005
    • Part of Columbia Asia group of hospitals
    • JCI and NABH accredited

    • Allogenic & Autologous bone marrow transplant
    • Separate HEPA filter with triple level air filtration in each room
    • Treated patients from Sweden, Nigeria, Kenya and Bangladesh
    Details
  • BLK Hospital
    Location
    Nearest Airport New Delhi ( 13 km)
    • Super-specialty tertiary care hospital established in year 1959
    • JCI and NABH accredited hospital in New Delhi
    • 125 critical care beds with 17 modular operation theatres

    • Asia's largest bone marrow transplant centre
    • More than 800 successful BMT including MUD(Match unrelated Donor)
    • Apheraesis Machine for extracting bone marrow cells
    Details
  • Apollo Health City
    Location
    Nearest Airport Hyderabad ( 35 km)
    • Multi-specialty hospital established in year 1988
    • Part of Apollo Hospitals group
    • JCI and NABH accredited
    Details
  • Kokilaben Dhirubhai Ambani Hospital
    Location
    Nearest Airport Mumbai ( 8 km)
    • Multi-specialty hospital established in year 2008
    • Care Pathway treatment model to improve medical outcomes
    • JCI and NABH accredited
    Details
  • American Oncology Institute
    Location
    Nearest Airport Hyderabad ( 40 km)
    • Flagship center of US-based Cancer Treatment Services International
    • International tumour board participates in treatment planning
    • Evidence based treatment planning for Precision Cancer Care

    • Autologous stem cell transplantation
    • Allogenic stem cell transplantation
    Details
  • FMRI
    Location
    Nearest Airport New Delhi ( 15 km)
    • Major hub hospital of Fortis Healthcare
    • NABH accredited hospital
    • 1000 bed Super Specialty hospital
    Details

 Bone Marrow Transplantation

The spongy tissue inside the bone is called as the bone marrow. Bone marrow is responsible for the generation of various types of blood cells like RBCs, WBCs and platelets that carry out various important functions. Due to certain diseases affecting the bone marrow, the production of blood cells is interfered with, leading to various serious and potentially fatal complications. In these situations, bone marrow transplantation is the only option to save one’s life.

Now let’s look at the various disorders that can affect the bone marrow:

The most common disorders that affect the bone marrow are the various types of bone marrow cancer. Some of the most important types of Bone Marrow Cancer are:

1. Multiple Myeloma occurs in the plasma cells and is the most common. It is predominantly seen in males over the age of 65.

2. Lymphomas are of two types- Hodgkins and Non-Hodgkins lymphomas. Increased age, exposure to chemicals, radiation, chemotherapy, HIV infections, obesity etc are known risk factors.

3. Leukaemia is of two types-Myeloid or lymphocytic and could be acute or chronic. Acute myeloid leukaemia (AML), chronic myeloid leukaemia (CML), acute lymphocytic leukaemia (ALL) and chronic lymphocytic leukaemia (CLL).

Symptoms of bone marrow cancer:

Symptoms may vary depending upon the type of cancer and may vary from person to person. Some of the common symptoms are:

• Persistent and recurrent fever

• Loss of weight

• Loss of appetite

• Fatigue

• Pain in the back

• Tenderness of the bones

• Swelling of the bones 

• Increased susceptibility to fractures of the bone

• Anaemia

• Recurrent infections

• Shortness of the breath

There are certain other diseases affecting the bone marrow that could warrant bone marrow transplantation. Some of them are:

• Aplastic anaemia

• Thalassemia’s

• Sickle cell anaemia

• Bone Marrow depression resulting from radiation or chemotherapy treatments

All these situations are dire and the patients require transplantation of the bone marrow at the earliest. Bone marrow transplantation procedure is undertaken in all major medical institutions around the world but the cost of the procedure varies significantly from country to country. Bone Marrow transplant cost in India is one of the lowest among medically advanced countries where the facilities are available. There are many super speciality hospitals that offer bone marrow transplant in India with a very high degree of success.

Types of bone marrow/Stem cell transplant and bone marrow transplant procedure:

There are various methods of bone marrow transplant depending on the source of the bone marrow:

• Autologous transplant: In an autologous transplant, the bone marrow is sourced from one’s own body and is ideal for situations where the patient may suffer from bone marrow depression because of radiation or chemotherapy. Functional stem cells are sourced from the large bones prior to the treatment and reintroduced into the body after the treatment is over.

• Allogeneic transplant: In an allogeneic transplant, bone marrow donation is done by another person who is genetically similar to the person who needs the transplant. Usually, close relatives like siblings, parents etc are the ideal donors but in certain cases, non-relatives may also qualify as potential donors. The bone marrow is harvested from the donor by using special syringes and needles from the hip bones under general anaesthesia. It is then transplanted to the recipient. 

• Cord blood transplant: Placental cord blood is harvested and stored for potential use in the future. These placental stem cells are then used if any necessities arise in the future.

• Peripheral blood stem cell transplant: done by a process called Apheresis where blood is taken out from the donor to extract the stem cells by passing it through special apparatus through an IV line starting from one arm and reintroduced into the body through an IV line in the other arm. The procedure is repeated until an adequate amount of stem cells are harvested. These stem cells are transplanted to the recipients for the regeneration of a healthy bone marrow.

Prior to transplantation procedure, radiation or chemotherapy is performed with the aim of destroying the diseased bone marrow and other cancer cells to make space for the transplanted bone marrow. Immuno-suppressants are also administered to reduce the immunity of the body to prevent the rejection of the bone marrow graft.

Risks and complications:

• Graft Versus Host Disease (GVHD) where donor cells attack the recipient's body cells

• Graft failure

• Occurrence of internal Bleeding problems

• Development of cataracts

• Anaemia 

• Side effects like decreased blood pressure, headaches, nausea, pain, shortness of breath, chills, fever might occur frequently

Dos and Don’ts:

Dos:

• Take medicines as prescribed

• Follow guidelines prescribed for healthy diet and food handling

• Give enough rest to the body

Don’ts:

• Don’t expose yourself to situations that can cause an infection

• Don’t ignore the mildest of infections

• Don’t ignore symptoms of GVHD like skin blisters, rashes, nausea, jaundice etc.